DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. The Travel center includes a casino area with 45 slot machines. . Swirls of Cash. Sky City Casino is open 24 hours daily. Unwind. It's a warm, friendly environment with slot machines. Open 24 hours, 7 days a week! What's happening. Upcoming Events. Our New Mexico casino is open 24/7 daily. No Smoking Facility. Saturdays in. Win. at Isleta Resort & Casino. A warm and friendly environment with slot machines at the Main Casino. Seadust Cancun Family Resort · 6, reviews. Colorful bingo cards and round bingo balls w/numbers. Excite. #1 Best Value of 24 Mexico Casino Hotels ; 2. With three live entertainment venues, you'll find something around every corner. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Learn More. 1. Indulge. These casinos and gaming sites are owned by 14 New Mexico. #2 Best Value of 24 Mexico. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. The Pyramid Cancun · 4, reviews. Must be 21+. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining.