Swirls of Cash. #1 Best Value of 24 Mexico Casino Hotels ; 2. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. at Isleta Resort & Casino. 1. #2 Best Value of 24 Mexico. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Upcoming Events. Must be 21+. Saturdays in. The Pyramid Cancun · 4, reviews. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Open 24 hours, 7 days a week! What's happening. Seadust Cancun Family Resort · 6, reviews. . Unwind. With three live entertainment venues, you'll find something around every corner. Excite. Our New Mexico casino is open 24/7 daily. These casinos and gaming sites are owned by 14 New Mexico. Sky City Casino is open 24 hours daily. It's a warm, friendly environment with slot machines. Colorful bingo cards and round bingo balls w/numbers. The Travel center includes a casino area with 45 slot machines. No Smoking Facility. Win. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Indulge. A warm and friendly environment with slot machines at the Main Casino. Learn More.